- Title
- Measurement of Cumulative Physiological Dysregulation in an Older Population
- Author(s)
- Christopher L. Seplaki Christopher Seplaki (Princeton University)
- Noreen Goldman Noreen Goldman (Princeton University)
- Maxine Weinstein Maxine Weinstein (Georgetown University)
- Yu-Hsuan Lin Yu-Hsuan Lin (Bureau of Health Promotion, Center for Population and Survey Research, Department of Health, Taichung, Taiwan)
- Abstract
- Theories of allostatic load postulate that an important pathway connecting the social environment with health involves biological responses to stressful stimuli and subsequent dysregulation of interrelated physiological systems. We formulate a new measure for cumulative physiological dysregulation using a grade of membership model estimated with biodemographic data from a national sample of older Taiwanese. We investigate associations between the measure and physical, psychological, and cognitive function. The results provide insights into the relationships between a set of biological profiles and various health outcomes, identify limitations of earlier approaches, and underscore next steps in the development of improved formulations of physiological dysregulation.
- Creation Date
- 2004-02
- Section URL ID
- OPR
- Paper Number
- opr0402.pdf
- URL
- https://web.archive.org/web/20150906192042/http://opr.princeton.edu/papers/opr0402.pdf
- File Function
- Jel
- I10
- Keyword(s)
- Suppress
- false
- Series
- 11